Sydenham chorea is the most common cause of acute chorea in children worldwide and is characterized by a random and continuous flow of contractions that spreads rapidly and becomes generalized. Evidence suggests that Sydenham chorea results from Streptococcus-induced antibodies that cross-react with central nervous system antigens. Neuropsychiatric symptoms, such as obsessions, compulsions, hyperactivity, and attention disorder, as well as depression, are often present in patients with Sydenham chorea.
Apr. 07, 2021