Transverse myelitis is part of a spectrum of demyelinating disease but has unique features that differentiate it from multiple sclerosis. The spinal cord damage in acute complete transverse myelitis generally affects all cord functions, and the symptoms are typically more severe than in typical cord lesions of multiple sclerosis. The first symptoms in transverse myelitis are ascending paresthesias or back pain at the level of the myelitis, plus leg weakness and sphincter dysfunction. Tingling or paresthesias in the feet soon progress to loss of pain, temperature, and vibration sensation, and then halt at a sensory level, usually thoracic (approximately 80%).
Aug. 05, 2016