Neuroleptic malignant syndrome
Neuroleptic malignant syndrome (NMS) is a life-threatening condition that should be suspected in any patient taking a dopamine receptor-blocking drug who has a high fever or decline in level of alertness. DSM IV criteria for diagnosing NMS include severe rigidity and fever accompanied by 2 of 10 minor features, including diaphoresis, dysphagia, tremor, incontinence, altered mentation, mutism, tachycardia, elevated or labile blood pressure, leukocytosis, and elevated creatine phosphokinase.
Mar. 13, 2021