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Base of the skull of a male acromegalic patient

Note the enlarged sella tursica and the elongated and thinned posterior clinoid plate. (A) enlarged pituitary fossa; (B) perforation in the elongated posterior clinoid plate; (C) atrophied optic nerves; (D) sixth cranial nerve (abducens). (Source: Brooks H. Acromegalia. Arch Neurol Psychopathol 1898;1[3]:485-678. Plate V.)