Movement Disorders
Multiple system atrophy
May. 22, 2024
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Toll Free (U.S. + Canada): 800-452-2400
US Number: +1-619-640-4660
Support: service@medlink.com
Editor: editor@medlink.com
ISSN: 2831-9125
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The poliovirus genome consists of a single-stranded, positive-sense polarity RNA molecule, which encodes a single polyprotein. The 5' non-translated region (NTR) harbors two functional domains, the cloverleaf and the internal ribosome entry site (IRES), and is covalently linked to the viral protein VPg. The 3'NTR is polyadenylated. (Source: De Jesus NH. Epidemics to eradication: the modern history of poliomyelitis. Virol J 2007;4:70. Creative Commons Attribution License [CC BY], creativecommons.org/licenses/by/2.0.)