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Brain imaging in patient with schizencephaly and longstanding hemiparesis

Brain imaging in an 85-year-old with schizencephaly with longstanding hemiparesis previously misdiagnosed as poliomyelitis. (A) CT brain without contrast showing inferior to superior sequence (shown left to right) of right-sided schizencephaly extending from the cortex to the right lateral ventricle. (B) MRI brain without contrast (axial T2 FLAIR) showing inferior to superior sequence (shown left to right) of right-sided schizencephaly extending from the cortex to the lateral ventricle and hypoplasia of the corpus callosum. (C) MRI brain without contrast (axial T1) showing margins of the schizencephaly defect lined with dysplastic gray matter. Arrows indicate a cleft extending from the right cerebral cortex into the lateral ventricle. (From: Guo Z, Scripko PD, Gertz AM. Open lip schizencephaly misdiagnosed as paralytic poliomyelitis in an 85-year-old: a case report. Clin Case Rep 2025;13[6]:e70556. Creative Commons Attribution 4.0 International [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.)

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Associated Disorders

  • Aseptic meningitis
  • Bulbar polio
  • Bulbospinal polio
  • Infantile paralysis
  • Nonparalytic polio
  • Paralytic polio
  • Polioencephalitis
  • Post-polio progressive muscular atrophy
  • Post-polio syndrome
  • Spinal paralytic polio