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Superficial siderosis: CD68-positive macrophages in superficial cortex

Superficial cortical tissue from the right frontal lobe (CD68 immunohistochemistry). Superficially located within the cortex, CD68-positive macrophages can be observed (arrowheads). (Source: Friedauer L, Foerch C, Steinbach J, et al. The acute superficial siderosis syndrome: clinical entity, imaging findings, and histopathology. Cerebellum 2023;22[2]:296-304. Creative Commons Attribution 4.0 International [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.)

Associated Disorders

  • Ataxia
  • Peripheral vestibular disorders
  • Sensorineural hearing loss
  • Subarachnoid hemorrhage