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Transmission electron micrograph of a microcolony of N. meningitidis after high pressure freezing and freeze substitution (2)

Transmission electron micrograph shows plasma membrane protrusions embedded in a meshwork of bacterial type IV pili labeled with immunogold. Abbreviation: T4P, bacterial type IV pili. Scale bars, 200 nm and 50 nm. (Source: Charles-Orszag A, Tsai FC, Bonazzi D, et al. Adhesion to nanofibers drives cell membrane remodeling through one-dimensional wetting. Nat Commun 2018;9[1]:4450. Creative Commons Attribution 4.0 International License, http://creativecommons.org/licenses/by/4.0.)

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Associated Disorders

  • asplenia
  • deficiency of a terminal complement component (C5-9)
  • deficiency of properdin