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Purulent exudate over the lateral surface of the brain in a fatal case of meningococcal meningitis

Note how the sulci are obscured by the exudate. (Source: Koplik H. The diseases of infancy and childhood designed for the use of students and practitioners of medicine. Fourth edition. Philadelphia and New York: Lea & Fibinger, 1918. Image edited and restored by Dr. Douglas J Lanska.)

Associated Disorders

  • asplenia
  • deficiency of a terminal complement component (C5-9)
  • deficiency of properdin