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Cobalamin (vitamin B12)

Cobalamin is a complex molecule at the core of which is a corrin ring: a tetrapyrrole structurally homologous to heme but with a cobalt atom, rather than iron, at its center. This illustration shows the chemical structures of various vitamers. (Figure by Alsosaid 1987, 2019. Courtesy of Wikimedia Commons. Creative Commons Attribution-Share Alike 4.0 International license.)

Associated Disorders

  • Alcohol-tobacco amblyopia
  • Cerebral vascular disease
  • Dementia
  • Depression
  • Developmental delay
  • Folate deficiency
  • Gastric resection
  • Glossitis
  • Imerslund-Grasbeck syndrome
  • Malabsorption
  • Megaloblastic anemia
  • Myelopathy
  • Optic neuropathy
  • Pernicious anemia
  • Polyneuropathy
  • Regional enteritis
  • Subacute combined degeneration of the spinal cord