Neuropharmacology & Neurotherapeutics
Anti-CGRP monoclonal antibodies for prevention of migraine
Mar. 24, 2021
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Normal cortical layer organization in sham (top row) and loss of any cellular layer organization in exencephaly (bottom row) (left to right in each row: 10x, 20x, and 40x, hematoxylin and eosin). Abbreviations: MZ: marginal zone; CP: cortical plate; SP: sub plate; IZ: intermediate zone. (Source: Oria M, Duru S, Figueira RL, et al. Cell necrosis, intrinsic apoptosis and senescence contribute to the progression of exencephaly to anencephaly in a mice model of congenital chranioschisis. Cell Death Dis 2019;10:721. Creative Commons Attribution [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.)