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Macro-ovalocytes

Peripheral blood smear of a patient with pernicious anemia showing many macro-ovalocytes (Leishman stain, 100X, oil immersion). (Source: Ramanathan et al 2017. Creative Commons Attribution License: creativecommons.org/licenses/by/3.0.)

Associated Disorders

  • Alcohol-tobacco amblyopia
  • Cerebral vascular disease
  • Dementia
  • Depression
  • Developmental delay
  • Folate deficiency
  • Gastric resection
  • Glossitis
  • Imerslund-Grasbeck syndrome
  • Malabsorption
  • Megaloblastic anemia
  • Myelopathy
  • Optic neuropathy
  • Pernicious anemia
  • Polyneuropathy
  • Regional enteritis
  • Subacute combined degeneration of the spinal cord