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Areas of reduced density in subcortical white matter consistent with extrapontine myelinolysis (CT)

CT scan of the head showing scattered areas of reduced density in the subcortical white matter, including the frontal lobes and right parietal lobe, consistent with extrapontine myelinolysis. This 40-year-old woman with chronic alcoholism presented with intractable headache for 3 days and progressively worsening unsteady gait requiring a wheelchair to ambulate. Electrolyte levels were normal. Central pontine myelinolysis and extrapontine myelinolysis were attributed to alcohol withdrawal. (Source: Jamil M, Salam A, Joseph Benher BM, Rehman S, Jamil J, Suleyman G. A case of alcohol withdrawal-induced central and extrapontine myelinolysis. Cureus 2023;15[7]:e41640. Creative Commons Attribution 4.0 International [CC BY 4.0] license,

Associated Disorders

  • Alcoholism
  • Extrapontine myelinolysis
  • Hyperosmolar hyperglycemic state
  • Hypokalemia
  • Malnutrition
  • Osmotic myelinolysis