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Hypointense central pons lesion in hypomagnesemia (axial T2 MRI)

Axial T2-weighted MRI sequence showing a hyperintense lesion in the central pons in a normonatremic woman with severe hypomagnesemia. (Source: Romero Calvo L, Garcia-Blanco MJ, Valenzuela F, Álvarez Granda J. Osmotic demyelination syndrome in a normonatremic patient under treatment with proton pump inhibitors. Cureus 2023;15[8]:e44472. Creative Commons Attribution 4.0 International [CC BY 4.0] license,

Associated Disorders

  • Alcoholism
  • Extrapontine myelinolysis
  • Hyperosmolar hyperglycemic state
  • Hypokalemia
  • Malnutrition
  • Osmotic myelinolysis