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Man showing the characteristic appearances of acromegaly

A 52-year-old man with acromegaly. Note the brow protrusion, large widened nose, thick lips, coarse facial features, large hands, and the widened, thickened, and stubby fingers. (Historic image from St Bartholomew's Hospital Photographic Society. Photograph restored by Douglas J Lanska MD. Courtesy of the Wellcome Library. Creative Commons Attribution 4.0 International license [CC BY 4.0].)