Abnormalities of tetrahydrobiopterin metabolism
Dec. 02, 2021
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André René Roussimoff (1946-1993), better known as André the Giant, was a French professional wrestler and actor. Roussimoff at this point showed manifestations of gigantism and some early manifestations of acromegaly. Note the thickened nose and large chin. (Public domain. Courtesy of Wikimedia Commons.)