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Pituitary adenoma from a 22-year-old man with acromegaly

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(Hematoxylin and Eosin, x 100) The patient underwent transsphenoidal surgery with complete tumor resection. Histological examination showed a highly vascularized pituitary adenoma with a diffuse (solid) growth pattern. Higher magnification in this image shows uniform cells with broad eosinophilic cytoplasm and round-to-oval nuclei. (Source: Gosau M, Vogel C, Moralis A, Proff P, Kleinheinz J, Driemel O. Mandibular prognathism caused by acromegaly - a surgical orthodontic case. Head Face Med 2009;5:16. Creative Commons Attribution 2.0 License, http://creativecommons.org/licenses/by/2.0. Figure edited by Dr. Douglas J Lanska to improve detail and contrast.)