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Prognathism, prominent supraorbital ridges, and facial soft tissues are evident, as are the large hands. (Contributed by Dr. Sherman Stein.)
Sep. 12, 2021
Neuropharmacology & Neurotherapeutics
Aug. 31, 2021
Behavioral & Cognitive Disorders
Cognitive impairment is a common feature of multiple sclerosis and often leads to declines in the ability to initiate and carry out instrumental activities of daily living. Cognitive impairment in multiple sclerosis affects most cognitive domains, but processing speed, visual learning, and short-term memory deficits are most common. Neuropsychiatric symptoms are common, with lifetime prevalence rates of depression approaching 50%.
Jun. 09, 2020
Jun. 23, 2021
Childhood Degenerative & Metabolic Disorders
The ketogenic diet is a medical treatment for intractable epilepsy and should only be administered under direct medical supervision. It is based on the premise that in the setting of limited carbohydrates, the body will preferentially turn to oxidation of fat for fuel. Patients require regular medical care, with frequent neurologic and dietary follow-up management.
Apr. 16, 2021
Multiple sclerosis is caused by immune attack against brain cells, with damage from demyelination and destruction of oligodendroglia, along with damage to axons and neurons. Cortical disruption affects cognition and multiple central nervous system functions. MS differs from other autoimmune diseases in that there is no proven target antigen.
Jul. 18, 2017
Sep. 16, 2020
Stroke & Vascular Disorders
Reversible cerebral vasoconstriction syndromes (RCVS) are characterized by recurrent, severe “thunderclap” headaches and multifocal cerebral arterial narrowing and dilatation, often complicated by ischemic or hemorrhagic strokes or reversible brain edema. RCVS affects young individuals, mostly women, and have been associated with diverse conditions such as pregnancy, migraine, vasoconstrictive drug use, pheochromocytoma, and neurosurgical procedures. The prognosis is usually excellent, with most patients recovering completely or near-completely within days to weeks.
Apr. 05, 2020