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Bone marrow in pernicious anemia

This photomicrograph reveals typical histopathologic details exhibited by a bone marrow tissue sample indicative of megaloblastic anemia as seen in pernicious anemia. Pernicious anemia is the result of an autoimmune disease in which antibodies attack gastric cells, resulting in impaired production of intrinsic factor that is critical in the absorption of vitamin B12. (Source: Centers for Disease Control and Prevention Public Health Image Library. Public domain.)

Associated Disorders

  • Alcohol-tobacco amblyopia
  • Cerebral vascular disease
  • Dementia
  • Depression
  • Developmental delay
  • Folate deficiency
  • Gastric resection
  • Glossitis
  • Imerslund-Grasbeck syndrome
  • Malabsorption
  • Megaloblastic anemia
  • Myelopathy
  • Optic neuropathy
  • Pernicious anemia
  • Polyneuropathy
  • Regional enteritis
  • Subacute combined degeneration of the spinal cord