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In 1923, following the earlier work of Adolph M Hanson, Collip isolated parathyroid hormone from crude glandular extracts. (Courtesy of Wikipedia. Public domain.)
Jun. 01, 2020
Thiamine deficiency causes loss of appetite, weakness, pain in the limbs, shortness of breath, and swollen feet or legs. Cardiac failure can occur in severe cases. Dietary deficiencies or alcoholism are common causes. Beriberi, Wernicke encephalopathy, and Korsakoff syndrome are related disorders.
Feb. 26, 2021
Epilepsy & Seizures
Benign familial and nonfamilial infantile seizures are characterized by seizure onset in the first year of life, remission by 2 years of life, and the absence of neurodevelopmental sequelae. Benign familial infantile seizures and benign nonfamilial infantile seizures are distinct syndromes with overlapping clinical presentations. Family history, genetic studies, and at times seizure semiology and EEG can be used to distinguish these syndromes from each other, though these are often unreliable.
Apr. 09, 2019
Oct. 16, 2020
Neuropharmacology & Neurotherapeutics
Sep. 04, 2021
Malignant hyperthermia is a hypermetabolic response to potent inhalational agents and/or succinylcholine that can lead to death. Most patients have no signs or symptoms prior to a malignant hyperthermia crisis. However, nonanesthesia-related cases of severe rhabdomyolysis linked to hereditary neuromuscular disorders or RYR1 or CACNA1S mutations are reported in the literature with increasing frequency.
Jun. 07, 2021
General Child Neurology
The authors explore current concepts related to back pain in the pediatric population. This article highlights the multifactorial nature of back pain
Sep. 29, 2020
Neurologic complications from systemic anticancer therapies impact quality of life and remain an important source of dose-limiting toxicity. These complications may result from the direct toxic effects of the drug on the nervous system or indirectly from metabolic derangements, inflammatory responses, or cerebrovascular disorders induced by the drugs. The neurotoxicities of chemotherapy are widely known, but targeted agents and immunotherapies are also associated with neurologic complications.
Dec. 19, 2020